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Natural Treatments

Natural Treatments and Nutritional Herb Supplements

How to Treat your Veins Naturally in St. Louis

plant leafBillions of people around the world have vein conditions such as varicose veins, spider veins, leg swelling and lymphedema, superficial phlebitis, postphlebitic syndrome, and venous ulcers. Some people have no symptoms, but a significant portion of the population suffers from symptoms such as leg heaviness, leg cramping and leg fatigue, swelling, and itching. Some people with these vein related conditions suffer debilitating pain. It is important that vein related medical signs and symptoms are properly evaluated by vein specialist to ensure that complications are avoided and necessary medical and surgical treatments are offered. Once a medical evaluation has ruled out complication of varicose veins, natural vericose vein treatment options should be discussed and conservative management should be started.

The cornerstone of conservative medical management include changes such as weight loss when appropriate, avoidance of sedentary lifestyle and wearing medical grade compression stockings.  A diet high in fiber and avoidance of straining with bowel movements certainly help with prevention and management of hemorrhoids and probably helps with varicose veins in thigh and pelvic area.  Natural dietary or nutritional supplements can help relief of symptoms related to vein conditions that have not responded to conservative management.  These plant derived natural vein treatment options or “herbal supplements” can compliment the lifestyle changes of conservative medical management as so may be “complementary treatments“.

Many more people have symptoms from the veins but are not bothered enough by their vein problems to seek medical or surgical treatments and may prefer instead to take dietary supplements for their vein problems until they are ready for more definitive treatments. There are some individuals who are religiously opposed to traditional medical treatment and chose to use mostly natural vein treatment like plant derived supplements unless there is an urgent medical reason. For all of the above circumstance over the counter and prescriptions dietary supplements are useful tool to relieve symptoms varicose and spider veins.

Nutritional Supplements That Help Vein Problems

Diosmin is the nutritional supplement that has the highest quality of evidence for its effectiveness on a broad range of vein problems. Diosmin is a bio-flavonoid that can be extracted in small quantities from many citrus fruits. It can also be synthesized from a closely related citrus flavonoid hesperidin. It is useful in varicose veins, chronic venous insufficiency, hemorrhoids, venous ulcer healing, and lymphedema. Diosmin has veno-tonic, anti-inflammatory, and antioxidant properties.

oranges-300x292RELIEF which stands for Reflux assEssment and quality of Life Improvement with micronized Flavonoids was a large multicenter randomized study that showed many benefits to varicose vein symptoms and disease for patients taking 450mg of micronized Diosmin plus 50 mg of micronized Hesperidin for six months. Reflux assessment and quality of life improvement with micronized Flavonoids in chronic venous insufficiency was a large multicenter randomized study that showed many benefits to varicose vein symptoms and disease for patients taking 450mg of micronized Diosmin plus 50 mg of micronized Hesperidin for six months. Diosmin significantly improved symptoms such as leg pain, heaviness, and cramps. Diosmin also improved leg edema or swelling and decreased leg circumference. Other studies have shown Diosmin improved venous ulcer healing, hemorrhoids, and lymphedema.

Vitamins and Dietary Supplements that May Help Varicose Veins

There are some other vitamin and herbal supplements available to treat varicose veins naturally, but their effectiveness and safety are less well known for the treatment of vein problems.   They have some studies that have shown some benefit but the studies are do not have the same scientific rigor or power that the Diosmin studies have shown so they are listed as may be of benefit. Also some of these dietary supplements may have some safety concerns. Vitamin C is an important nutrient for collagen synthesis and if there is a Vitamin C deficiency, supplementation with this vitamin will help improve vein strength. Pycnogenol, which is another bio flavonoid with anti-inflammatory properties, is an extract from French Maritime pine trees and has been shown to help cramping and aching. Rutin Glycoside is extracted from apples and other plants, but there is some concern it may cause liver damage and there have been reports of bleeding with Rutin. Horse chestnut seed extract may also have some benefits with the symptoms of varicose veins but is not well tolerated by the stomach.


What Have Nutritional Supplements Not Been Shown to Help?

Nutritional supplements do not make varicose or spider vein disappear nor do they change the appearance of varicose or spider veins. Also, supplements do not reverse the underlying disease process that causes varicose and spider veins. The greatest benefit of dietary supplements is relieving symptoms and helping with limb swelling.


What other names is Diosmin known by?

Diosmin is also referred to as: Bioflavonoid Complex, Bioflavonoid Concentrate, Citrus Bioflavonoid, and Daflon [supplement in Europe]. Diosmin is the principal ingredient in Vasculera, which is an FDA approved medical food.

 



Reference for Diosmin and Varicose Veins and Chronic Vein Insufficiency

Jantet Georges. RELIEF Study: First Consolidated European Data. Angiology. 2000.51;31-37 [Link Here]

Geroulakos G and Nicolaides AN. Controlled studies of Daflon 500 mg in chronic venous insufficiency. Angiology. 1994.45;549-53

Ibegbuna V, NicolaidesAN,Sowade O et al. Venous elasticity after treatment withDaflon 500 mg. Angiology. 1997.48;45-9

Carpentier PH and Mathieu M. Evaluation of clinical efficacy of a venotonic drug: lessons of a therapeutic trial with hemisynthetic diosmin in “heavy legs syndrome”. J Mal Vasc. 1998.23;106-12

Jantet Georges. RELIEF Study: First Consolidated European Data. Angiology. 2000.51;31-37

Ramelet AA. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001.52;S49-56

Jantet G and the Relief Study Group. Chronic Venous Insufficiency: Worldwide Results of the RELIEF Study. Angioogy. 2002.53;245-56

Danielsson G, Jungbeck C Peterson K and Norgren L. A randomized controlled trial of micronised purified flavonoid fraction vs placebo in patients with chronic venous disease. Eur J VascEndovasc Surg. 2002.23;73-6

Lyseng-Williamson KA and Perry CM. Micronised Purified Flavonoid Fraction: A review of its Use in Chronic Venous Insufficiency, Venous Ulcers and Haemorrhoids. Drugs. 2003.63;71-100


References for Diosmin Treatment of Leg Swelling and Lymphedema

Labrid C. A lymphatic function of Daflon 500 mg. Int Angiol. 1995.14;36-8

Olszewski W. Clinical efficacy of micronized purified flavonoid fraction (MPFF) in edema. Angiology. 2000.51;25-9

Ramelet AA. Pharmacologic aspects of a phlebotropic drug in CVI-asociated edema. Angiology. 2000.51;19-23


Reference for Diosmin and Diabetic Patients

Valensi PE, Behar A, de Champvallins MM et al. Effects of a purified micronized flavonoid fraction on capillary filtration in diabetic patients. Diabet med.1996.13;882-9


References for Diosmin and Venous Ulcers

Trent JT, Falabella A, Eaglstein WH, Kirsner RS Venous ulcers: pathophysiology and treatment options. Ostomy/wound Management [2005, 51(5):38-54; quiz 55-6] [Link Here]

Guilhou JJ, Dereure O, Marzin L et al. Efficacy of Daflon 500 mg in venous leg ulcer healing: a double-blind, randomized, controlled versus placebo trial in 107 patients. Angiology. 1997.48;77085

Roztocil K, Stvrtinova V, and Strejcek J. Efficacy of a 6-month treatment with Daflon500 mg in patients with venous leg ulcers associated with chronic venous insufficiency. IntAngiol. 2003.22;24-31

Lyseng-Williamson KA and Perry CM. Micronised Purified Flavonoid Fraction: A review of its Use in Chronic Venous Insufficiency, Venous Ulcers and Haemorrhoids. Drugs. 2003.63;71-100

Trent JT, Falabella A, Eaglstein WH, Kirsner RS
Venous ulcers: pathophysiology and treatment options.
Ostomy/wound Management [2005, 51(5):38-54; quiz 55-6] Smith PC. Daflon 500 mg and venous leg ulcer: new results from a meta-analysis. Angiology. 2005.56;S33-9


References for Diosmin and Hemorrhoids

Cospite M. Double-blind, placebo-controlled evaluation of clinical activity and safety of Daflon 500 mg in the treatment of acute hemorrhoids. Angiology. 1994 Jun; 45(6 Pt 2):566-73.

Godeberge P. Daflon 500 mg in the treatment of hemorrhoidal disease: a demonstrated efficacy in comparison with placebo. Angiology. 1994 Jun; 45(6 Pt 2):574-8.

Thanapongsathorn W and Vajrabukka T. Clinical trial of oral diosmin (Daflon) in the treatment of hemorrhoids. Dis Colon Rectum. 1992.35;1085-8

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